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Gene Expression Literature Summary
Assay
Age
Immunohistochemistry (whole mount)
4.5 DPC

17 matching records from 17 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Gata4  GATA binding protein 4   (Synonyms: Gata-4)
Results  Reference
1J:332401 Abuhashem A, Chivu AG, Zhao Y, Rice EJ, Siepel A, Danko CG, Hadjantonakis AK, RNA Pol II pausing facilitates phased pluripotency transitions by buffering transcription. Genes Dev. 2022 Aug 18;36(13-14):770-89
1J:238298 Acampora D, Omodei D, Petrosino G, Garofalo A, Savarese M, Nigro V, Di Giovannantonio LG, Mercadante V, Simeone A, Loss of the Otx2-Binding Site in the Nanog Promoter Affects the Integrity of Embryonic Stem Cell Subtypes and Specification of Inner Cell Mass-Derived Epiblast. Cell Rep. 2016 Jun 21;15(12):2651-64
1J:201276 Betschinger J, Nichols J, Dietmann S, Corrin PD, Paddison PJ, Smith A, Exit from pluripotency is gated by intracellular redistribution of the bHLH transcription factor Tfe3. Cell. 2013 Apr 11;153(2):335-47
1*J:226497 Brewer JR, Molotkov A, Mazot P, Hoch RV, Soriano P, Fgfr1 regulates development through the combinatorial use of signaling proteins. Genes Dev. 2015 Sep 1;29(17):1863-74
1J:199467 Do DV, Ueda J, Messerschmidt DM, Lorthongpanich C, Zhou Y, Feng B, Guo G, Lin PJ, Hossain MZ, Zhang W, Moh A, Wu Q, Robson P, Ng HH, Poellinger L, Knowles BB, Solter D, Fu XY, A genetic and developmental pathway from STAT3 to the OCT4-NANOG circuit is essential for maintenance of ICM lineages in vivo. Genes Dev. 2013 Jun 15;27(12):1378-90
1*J:143379 Hirasawa R, Sasaki H, Dynamic transition of Dnmt3b expression in mouse pre- and early post-implantation embryos. Gene Expr Patterns. 2009 Jan;9(1):27-30
1J:320699 Ichikawa T, Zhang HT, Panavaite L, Erzberger A, Fabreges D, Snajder R, Wolny A, Korotkevich E, Tsuchida-Straeten N, Hufnagel L, Kreshuk A, Hiiragi T, An ex vivo system to study cellular dynamics underlying mouse peri-implantation development. Dev Cell. 2022 Feb 7;57(3):373-386.e9
1*J:118937 Kaji K, Nichols J, Hendrich B, Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells. Development. 2007 Mar;134(6):1123-32
1*J:191065 Kang M, Piliszek A, Artus J, Hadjantonakis AK, FGF4 is required for lineage restriction and salt-and-pepper distribution of primitive endoderm factors but not their initial expression in the mouse. Development. 2013 Jan;140(2):267-79
1J:194241 Li C, Finkelstein D, Sherr CJ, Arf tumor suppressor and miR-205 regulate cell adhesion and formation of extraembryonic endoderm from pluripotent stem cells. Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):E1112-21
1*J:182713 McDonel P, Demmers J, Tan DW, Watt F, Hendrich BD, Sin3a is essential for the genome integrity and viability of pluripotent cells. Dev Biol. 2012 Mar 1;363(1):62-73
1J:260470 Meng Y, Moore R, Tao W, Smith ER, Tse JD, Caslini C, Xu XX, GATA6 phosphorylation by Erk1/2 propels exit from pluripotency and commitment to primitive endoderm. Dev Biol. 2018 Apr 1;436(1):55-65
1J:153637 Nichols J, Silva J, Roode M, Smith A, Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo. Development. 2009 Oct;136(19):3215-22
1*J:138816 Plusa B, Piliszek A, Frankenberg S, Artus J, Hadjantonakis AK, Distinct sequential cell behaviours direct primitive endoderm formation in the mouse blastocyst. Development. 2008 Sep;135(18):3081-91
1*J:268273 Simon CS, Zhang L, Wu T, Cai W, Saiz N, Nowotschin S, Cai CL, Hadjantonakis AK, A Gata4 nuclear GFP transcriptional reporter to study endoderm and cardiac development in the mouse. Biol Open. 2018 Dec 10;7(12):bio036517
1J:290083 Uyhazi KE, Yang Y, Liu N, Qi H, Huang XA, Mak W, Weatherbee SD, de Prisco N, Gennarino VA, Song X, Lin H, Pumilio proteins utilize distinct regulatory mechanisms to achieve complementary functions required for pluripotency and embryogenesis. Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):7851-7862
1J:228855 Wicklow E, Blij S, Frum T, Hirate Y, Lang RA, Sasaki H, Ralston A, HIPPO pathway members restrict SOX2 to the inner cell mass where it promotes ICM fates in the mouse blastocyst. PLoS Genet. 2014 Oct;10(10):e1004618

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory